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Recombinant Mouse Fibroblast Growth Factor-18
英文名:
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| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132686-10 μg | 0 | ¥3200 | ||||
| 1308132686-50 μg | 0 | ¥7800 |
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| 性狀 | Recombinant Mouse Fibroblast Growth Factor-18 是成熟軟骨細胞及其祖細胞的營養因子。
Synonyms rMuFGF-18; zFGF5; Fgf18 ; 重組小鼠成纖維細胞生長因子-18 Species Mouse Source E. coli Accession O89101 Gene ID 14172 Molecular Weight Approximately 20.1 kDa AA Sequence EENVDFRIHV ENQTRARDDV SRKQLRLYQL YSRTSGKHIQ VLGRRISARG EDGDKYAQLL VETDTFGSQV RIKGKETEFY LCMNRKGKLV GKPDGTSKEC VFIEKVLENN YTALMSAKYS GWYVGFTKKG RPRKGPKTRE NQQDVHFMKR YPKGQAELQK PFKYTTVTKR SR Biological Activity The ED50 is <0.5 μg/mL as measured by 3T3 cells, corresponding to a specific activity of >2.0 × 103 units/mg. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Mouse Fibroblast Growth Factor-18 (rMuFGF-18) to 100 μg/mL using ddH2O. Storage & Stability Lyophilized recombinant Mouse Fibroblast Growth Factor-18 (rMuFGF-18) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Mouse Fibroblast Growth Factor-18 (FGF18) is a trophic factor for mature chondrocytes and their progenitors[1]. FGF18 has been reported to have significant anabolic effects on cartilage. FGF18 plays a central role in skeletal growth and development. Mice lacking Fgf18 exhibit malformations in cartilage and bone, including delayed closure of the calvarial sutures, enlargement of the proliferating and hypertrophic zones in the growth plate of long bones, defects in joint development, and delays in osteogenic differentiation[2]. |
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