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Btk (C-term)
英文名：Rabbit Monoclonal IgG
Cas號(hào)：
Cas號(hào)：
檢測(cè)信息查詢
| 貨號(hào) | 規(guī)格 | 貨期 | 庫存 | 價(jià)格 | 促銷價(jià) | 訂購 |
| 1308113379-100ul | 現(xiàn)貨 | 0 | ￥0 |
| 別 名 | PR12, Nucleic acid-binding regulat o r y protein |
| Cas號(hào) | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 產(chǎn)品參數(shù) | 【產(chǎn)品介紹】Btk (Bruton tyrosine kinase also known as BPK
o r ATK) is a member of the TEC family of non-recept o r protein tyrosine kinase which includes Bmx, Itk a n d TEC. Btk is composed of a pleckstrin domain, an SH3 a n d SH2 domain, a catalytic kinase domain a n d a TEC homology domain (1). BTK plays a crucial role in B cell activation a n d development (2). Similar to Etk-TNFR2 interaction, Btk interacts with Fas, a member of the TNFR family involved in apoptosis in a lig a n d -independent manner (3) Mutations in the Btk gene have been linked to severe developmental blocks in human B-cell ontogeny leading to X-linked agammaglobulinemia (XLA). Patients with this disease are unusually prone to bacterial infection but not to viral infection. WB: 1:500 IP: 1:20 A. Western blot analysis on Daudi cell lysate using anti-Btk (C-term) RabMAb (cat. #1599-1), 1:500 dilution |
| 性狀 | 【反應(yīng)特異性】Human
【克隆 ID】Y440 【用途】WB , IP 【抗原分子量】77 kDa |
| 貯存 |
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