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Ezrin Rabbit Antibody
英文名：Rabbit Monoclonal IgG
Cas號：
Cas號：
檢測信息查詢
| 貨號 | 規(guī)格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308113566-100ul | 現(xiàn)貨 | 0 | ￥0 |
| 別 名 | p81, Cytovillin, Villin-2 |
| Cas號 | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 產(chǎn)品參數(shù) | 【產(chǎn)品介紹】Erzin, a member of the Ezrin, Radixin,
Moesin (ERM) family, is a linker protein located between cell surface recept o r s, adhesion molecules, a n d actin cytoskeleton (1-2). Ezrin activity is regulated by intramolecular interactions between N- a n d C-terminal ERM association domains (3). Erzin tyrosine phosph o r ylation can also be induced by EGF, PDGF a n d HGF stimulation. Erzin interacts with PI3-K protein kinase A a n d Rho (4). In response to epidermal growth fact o r (EGF) the microvillar c o r e protein ezrin is phosph o r ylated transiently to a high level on tyrosine residues in human epidermoid carcinoma A431 cells. Tyr145, lies in the N-terminal region of homology that is common to the b a n d 4.1-talin-ezrin protein family. This tyrosine residue a n d its vicinal amino acids are conserved throughout the family members, including radixin, moesin, a n d the two phosphotyrosine phosphatases, PTP H1 a n d PTP MEG, but not in b a n d 4.1 o r talin (5). WB: 1:1000 - 5000 ICC: 1:100 – 250 Flow Cytometry: 1:20 A. Western blot analysis on (A) 293, (B) A431 a n d (C) SH-SY5Y cell lysate using anti-Ezrin RabMAb (cat. # 2255-1), dilution 1:10,000. |
| 性狀 | 【反應特異性】Human , Mouse , Rat
【克隆 ID】EP924Y 【用途】WB , ICC , FC 【抗原分子量】81 kDa |
| 貯存 |
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