小程序掃碼下單
本網站銷售的所有產品僅用于工業應用或者科學研究等非醫療目的，不可用于人類或動物的臨床診斷或者治療，非藥用，非食用。
α-平滑肌肌動蛋白
英文名：Smooth Muscle
Cas號：
Cas號：
檢測信息查詢
| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308114365-100ul | 現貨 | 0 | ￥3575 |
| 別 名 | 平滑肌γ-肌動蛋白，γ-2-肌動蛋白，α-肌動蛋白-3 |
| Cas號 | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 產品參數 | 【產品介紹】Actins are highly conserved
proteins ubiquitously expressed in all eukaryotic cells. They comprise, along with microtubules, a maj o r component of the cytoskeleton. Actin has been found to be expressed in at least six isomeric f o r ms. It is expressed in heart a n d skeletal striated muscle tissue, a n d in certain smooth muscle tissues, regulating contractile potentials f o r these cells. It is also expressed in the cytoplasm of non-muscle cells, functioning to control cell structure a n d motility (1). Polymerization of globular actin (G-actin) leads to a structural filament (F-actin), whose f o r mation requires the Arp2/3 complex (2). It has been rep o r ted that actin is hyperphosph o r ylated in primary breast tum o r s (3). It has also been shown that actin dysfunction leads to certain types of heart failure (4). Smooth muscle alpha actin is of further interest because it is one of a few genes whose expression is relatively restricted to vascular smooth muscle cells. Furtherm o r e, expression of smooth muscle alpha actin is regulated by h o r mones a n d cell proliferation, a n d is altered by pathological conditions including oncogenic transf o r mation a n d atherosclerosis (5). Recommended Applications WB, IHC, IP, FC Applications and Recommended Dilution Factors WB: 1:1,000 - 5,000 IHC: 1:1000-2000 FC: 1:20 IP: 1:20 Species Reactivity * Human, Mouse, Rat * *Cross reactivity determined by western blot only. Products Data A. Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-a-Actin (Smooth Muscle) RabMAb (cat. #1184-1); shows positive staining of smooth muscle tissue. B. Immunohistochemical analysis of paraffin-embedded skeletal muscle tissue using anti-a-Actin (Smooth Muscle) RabMAb (cat. #1184-1); shows negative staining of skeletal muscle tissue. C. Western blot analysis on A431 cell lysate using anti-a-Actin (Smooth Muscle) RabMAb (catalog #1184-1). Specificity A synthetic peptide corresponding to N-terminus of human Actin was used as immunogen. This antibody only detects actin in smooth muscle in immunohistochemistry. |
| 性狀 | 【產品類型】兔單克隆抗體
【反應特異性】人類，小鼠，大鼠 【克隆ID 】 E184 【用途】 WB，IHC，FC，IP 【產品性狀】 【陽性對照】 【產品濃度】 【細胞定位】 【抗原分子量】 42 kDa的 |
| 貯存 | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
滬公網安備 31012002003054號