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HNF4 Alpha
英文名：HNF4A
Cas號：
Cas號：
檢測信息查詢
| 貨號 | 規(guī)格 | 貨期 | 庫存 | 價(jià)格 | 促銷價(jià) | 訂購 |
| 1308114410-100ul | 現(xiàn)貨 | 0 | ￥0 |
| 別 名 | HNF4A antibody, FLJ39654 antibody, HNF4 antibody, HNF4a7 antibody, HNF4a8 antibody, HNF4a9 antibody, HNF4alpha antibody, MODY antibody, MODY1 antibody, NR2A1 antibody, NR2A21 antibody, TCF antibody, TCF14 antibody, Hepatocyte nuclear factor 4-alpha antibo |
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| 產(chǎn)品參數(shù) | 【產(chǎn)品介紹】HNF4 (Hepatocyte Nuclear Factor 4) is a
nuclear receptor protein belonging to the steroid hormone receptor superfamily. HNF4 is commonly expressed in the liver and plays a critical role in liver development by establishing and maintaining hepatocyte differentiation (1). In human, two isoforms of HNF4 exists, alpha and gamma. HNF4 alpha is transcriptionally controlled transcription factor, which binds to DNA sites required for the transcription of alpha 1- antitrypsin, Apo CIII, transthyretin genes, and HNF1 alpha (2). HNF4 alpha interacts with PGC-1 to activate gluconeogenesis, leading to lipoprotein metabolism regulation (3). HNF4 alpha defects are known to cause type I diabetes (4). Recommended Applications WB, IHC, ICC, IP, FC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IHC: 1:100 - 250 ICC: 1:100 - 250 IP: 1:10 - 100 FC: 1:10 - 100 Species Reactivity Human Products Data Western blot analysis on (A) HepG2, (B) A549 and (C) SW480 cell lysates using anti-HNF4 Alpha RabMAb (cat. #2803-1). Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-HNF alpha RabMAb (cat. #2803-1). Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-HNF alpha RabMAb (cat. #2803-1). Immunofluorescent staining of HepG2 cells using anti-HNF4 alpha RabMAb (cat. #2803-1). Specificity A synthetic peptide corresponding to residues in human HNF4 Alpha was used as an immunogen. |
| 性狀 | 【產(chǎn)品類型】Rabbit Monoclonal Antibody
【反應(yīng)特異性】Human 【克隆 ID】EPR3648 【用途】WB , IHC , ICC , FC , IP 【產(chǎn)品性狀】 【陽性對照】 【產(chǎn)品濃度】 【細(xì)胞定位】 【抗原分子量】52kDa |
| 貯存 | Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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