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Recombinant Mouse Interleukin-10 (CHO-expressed)
英文名：
Cas號(hào)：
Cas號(hào)：
檢測(cè)信息查詢
| 貨號(hào) | 規(guī)格 | 貨期 | 庫(kù)存 | 價(jià)格 | 促銷價(jià) | 訂購(gòu) |
| 1308132598-10 μg | 0 | ￥4400 | ||||
| 1308132598-50 μg | 0 | ￥14800 |
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| 性狀 | Recombinant Mouse Interleukin-10 (CHO-expressed) 是一種有效的 CHO 細(xì)胞來源的抗炎細(xì)胞因子，作用于感染了神經(jīng)性冠狀病毒的小鼠，增強(qiáng)免疫介導(dǎo)的脫髓鞘作用。
Synonyms rMuIL-10; CSIF Species Mouse Source CHO Accession P18893 Gene ID 16153 Molecular Weight 21-23 kDa AA Sequence SRGQYSREDN NCTHFPVGQS HMLLELRTAF SQVKTFFQTK DQLDNILLTD SLMQDFKGYL GCQALSEMIQ FYLVEVMPQA EKHGPEIKEH LNSLGEKLKT LRMRLRRCHR FLPCENKSKA VEQVKSDFNK LQDQGVYKAM NEFDIFINCI EAYMMIKMKS Biological Activity The ED50 is <0.2 ng/mL as measured by MC/9 cells. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Murine Interleukin-10 (CHO-expressed) (rMuIL-10) to 100 μg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Murine Interleukin-10 (CHO-expressed) (rMuIL-10) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background The anti-inflammatory cytokine interleukin-10 (IL-10) is a pleiotropic cytokine that is produced in abundant quantities during most parasitic, bacterial, viral, and fungal diseases. IL-10 functions by dampening the innate or very early T cell immune response. Treatment with IL-10 may be useful adjunct therapy in some types of viral encephalitis. IL-10 primarily acts to suppress macrophages and dendritic cell (DC) function by inhibiting expression of major histocompatibility complex (MHC) class II and costimulatory molecules such as CD80/CD86 and production of proinflammatory cytokines and chemokines, including IL-12. IL-10 also has direct effects on T cells, inhibiting activation and cytokine expression. Production of IL-10 by highly activated virus-specific T cells raises the possibility that IL-10 functions via both autocrine and paracrine signaling to limit inflammation during acute phases of the disease[1]. |
| 貯存 |
- Recombinant Mouse Insulin-like Growth factor-1
- Recombinant Mouse Interferon-gamma
- Recombinant Mouse Interleukin-1 alpha
- Recombinant Mouse Interleukin-1 beta
- Recombinant Mouse Interleukin-10 (CHO-expressed)
- Recombinant Mouse Interleukin-11 (HEK293-expressed)
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- Recombinant Mouse Interleukin-13, His (CHO-expressed)
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