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Recombinant Mouse Interleukin-22
英文名：
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檢測信息查詢
| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132605-10 μg | 0 | ￥4800 | ||||
| 1308132605-50 μg | 0 | ￥16200 |
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| 性狀 | Recombinant Mouse Interleukin-22 通過保護腸干細胞免受免疫介導的組織損傷從而在上皮再生和抑制慢性炎癥反應中起重要作用。
Synonyms rMuIL-22; Cytokine Zcyto 18; IL-TIF Species Mouse Source E. coli Accession Q9JJY9 Gene ID 50929 Molecular Weight Approximately 16.8 kDa AA Sequence LPVNTRCKLE VSNFQQPYIV NRTFMLAKEA SLADNNTDVR LIGEKLFRGV SAKDQCYLMK QVLNFTLEDV LLPQSDRFQP YMQEVVPFLT KLSNQLSSCH ISGDDQNIQK NVRRLKETVK KLGESGEIKA IGELDLLFMS LRNACV Biological Activity The ED50 is <0.5 ng/mL as measured by Colo205 cells. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Murine Interleukin-22 (rMuIL-22) to 100 μg/mL using ddH2O or PBS. Storage & Stability Lyophilized recombinant Murine Interleukin-22 (rMuIL-22) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Interleukin-22 (IL-22) is a member of the IL-10 family of cytokines, expressed predominantly by subsets of innate lymphoid cells (ILCs) and activated T cells, including T helper 1 (TH1) cells, TH17 cells and TH22 cells. IL-22 can be recognized by a heterodimeric receptor complex that consists of two transmembrane subunits: IL-22R1 and IL-10R2. The binding of IL-22 to its receptor activates the JAK/STAT and MAPK signaling pathway, resulting in gene expression or repression. Since the IL-10R2 is shared by five cytokines (IL-10, IL-22, IL-26, IL-28, and IL-29) and is widely expressed in most cells, the expression of the IL-22R1 determines whether a cell is the target of IL-22. IL-22 has a considerable therapeutic potential in graft-versus-host disease (GVHD), which is a frequent and challenging complication following allogeneic stem cell transplantation[1]. |
| 貯存 |
- 抗氧化劑B215
- Recombinant Mouse Interleukin-13, His (CHO-expressed)
- Recombinant Mouse Interleukin-2
- Recombinant Mouse Interleukin-21
- Recombinant Mouse Interleukin-22
- Recombinant Mouse Interleukin-4 (CHO-expressed)
- Recombinant Mouse Interleukin-5
- Recombinant Mouse Interleukin-7 (CHO-expressed)
- Recombinant Mouse Interleukin-9
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