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Recombinant Mouse CNTF
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檢測信息查詢
| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132666-10 μg | 0 | ￥2800 | ||||
| 1308132666-50 μg | 0 | ￥7800 |
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| 性狀 | Recombinant Mouse CNTF是一種多能性神經營養因子，可保護視網膜錐細胞和視桿細胞的光感受器。
Synonyms rMuCNTF; Ciliary Neurotrophic Factor ; 重組小鼠睫狀神經營養因子 (CNTF) Species Mouse Source E. coli Accession P51642 Gene ID 12803 Molecular Weight Approximately 22.6 kDa AA Sequence AFAEQSPLTL HRRDLCSRSI WLARKIRSDL TALMESYVKH QGLNKNISLD SVDGVPVAST DRWSEMTEAE RLQENLQAYR TFQGMLTKLL EDQRVHFTPT EGDFHQAIHT LTLQVSAFAY QLEELMALLE QKVPEKEADG MPVTIGDGGL FEKKLWGLKV LQELSQWTVR SIHDLRVISS HHMGISAHES HYGAKQM Biological Activity The ED50 is <30 ng/mL as measured by its ability to induce alkaline phosphatase production by TF-1 cells. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Mouse CNTF (rMuCNTF) to 100 μg/mL using ddH2O. Storage & Stability Lyophilized recombinant Mouse CNTF (rMuCNTF) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Ciliary Neurotrophic Factor (CNTF) is an extracellular signaling protein in the neuroretinal and the interphotoreceptor matrix, which is associated with the membranes of the RPE, Muller and photoreceptor cells[1]. CNTF has neuroprotective effects on a variety of central and also peripheral nervous system neurons. Because it promotes differentiation and maturation of oligodendrocyte precursor cells to oligodendrocytes under in vitro conditions and thus improves remyelination. Importantly, it also increases the survival of mature oligodendrocytes[2]. |
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