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Recombinant Human Interleukin-4 Receptor (HEK293-expressed)
英文名:
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| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132733-10 μg | 0 | ¥3600 | ||||
| 1308132733-50 μg | 0 | ¥12800 |
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| 性狀 | Recombinant Human Interleukin-4 Receptor (HEK293-expressed) 是I型跨膜蛋白,可以結合白細胞介素-4和白細胞介素-13。
Synonyms rHuIL-4R; IL4R; IL-4RA; CD124 ; 重組人白細胞介素-4受體 (HEK293表達) Species Human Source HEK 293 Accession P24394 Gene ID 3566 Molecular Weight 40-45 kDa AA Sequence GNMKVLQEPT CVSDYMSIST CEWKMNGPTN CSTELRLLYQ LVFLLSEAHT CIPENNGGAG CVCHLLMDDV VSADNYTLDL WAGQQLLWKG SFKPSEHVKP RAPGNLTVHT NVSDTLLLTW SNPYPPDNYL YNHLTYAVNI WSENDPADFR IYNVTYLEPS LRIAASTLKS GISYRARVRA WAQCYNTTWS EWSPSTKWHN SYREPFEQH Biological Activity The ED50 is <70 ng/mL as measured by TF-1 cells. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Interleukin-4 Receptor (HEK293-expressed) (rHuIL-4R) to 100 μg/mL using ddH2O or PBS. Storage & Stability Lyophilized recombinant Human Interleukin-4 Receptor (HEK293-expressed) (rHuIL-4R) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background The effect of IL-4 signaling is mediated through the IL-4 receptor alpha chain (IL-4Rα). Upon binding to its ligand, IL-4Rα dimerizes either with the common gamma chain (γc) to produce the type-1 signaling complex located mainly on hematopoietic cells, or with the IL-13 receptor alpha 1 (IL-13Rα1) to produce the type-2 complex, which is expressed also on non-hematopoietic cells[1]. |
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