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Recombinant Human I-TAC/CXCL11 (HEK293-expressed)
英文名：
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檢測信息查詢
| 貨號 | 規(guī)格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132741-10 μg | 0 | ￥3200 | ||||
| 1308132741-50 μg | 0 | ￥7800 |
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| 性狀 | Recombinant Human I-TAC/CXCL11 (HEK293-expressed) 是屬于CXC趨化因子家族的細胞因子，其可被IFN-γ及其CXCR3受體強烈誘導。
Synonyms rHuI-TAC/CXCL11; C-X-C motif chemokine 11; Beta-R1; H174; IP-9; SCYB11 ; 重組人I-TAC/CXCL11 (HEK293表達) Species Human Source HEK 293 Accession O14625 Gene ID 6373 Molecular Weight Approximately 8.3 kDa AA Sequence FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLIIKKVER KNF Biological Activity The ED50 is <0.5 μg/mL as measured by CHO-K1/Gα15/hCXCR3 cells (human Gα15 and human CXCR3 stably expressed in CHO-K1 cells). Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human I-TAC/CXCL11 (HEK293-expressed) (rHuI-TAC/CXCL11) to 100 μg/mL using ddH2O or PBS. Storage & Stability Lyophilized recombinant Human I-TAC/CXCL11 (HEK293-expressed) (rHuI-TAC/CXCL11) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background CXCL11 is produced by a variety of cells including leukocytes, fibroblasts, and endothelial cells upon stimulation with interferons (IFNs). Simultaneous stimulation of fibroblasts or endothelial cells with IFN-γ and interleukin-1β or the TLR3 ligand double-stranded RNA resulted in a synergistic increase of CXCL11 production. CXCL11 attracts activated T-helper 1 (Th1) lymphocytes and natural killer (NK) cells. Like CXCL9 or monokine induced by IFN-γ (Mig) and CXCL10 or IFN-γ–inducible protein-10 (IP-10), CXCL11 signals through CXC chemokine receptor 3 (CXCR3)[1]. |
| 貯存 |
- Recombinant Human Interleukin-8/CXCL8
- Recombinant Rat IP-10/CRG-2/CXCL10 (HEK293-expressed)
- Recombinant Human IP-10/CXCL10
- Recombinant Mouse IP-10/CXCL10
- Recombinant Human I-TAC/CXCL11 (HEK293-expressed)
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