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Recombinant Human MIP-4/CCL18
英文名:
Cas號(hào):
Cas號(hào):
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| 貨號(hào) | 規(guī)格 | 貨期 | 庫(kù)存 | 價(jià)格 | 促銷(xiāo)價(jià) | 訂購(gòu) |
| 1308132778-10 μg | 0 | ¥4800 | ||||
| 1308132778-50 μg | 0 | ¥10800 |
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| 性狀 | Recombinant Human MIP-4/CCL18 是一種 CC 趨化因子配體,為中性的 CCR3 拮抗劑,與炎癥反應(yīng)有關(guān)。
Synonyms rHuMIP-4/CCL18; C-C motif chemokine 18; AMAC-1; SCYA18 ; 重組人 MIP-4/CCL18 Species Human Source E. coli Accession P55774 Gene ID 6362 Molecular Weight Approximately 7.9 kDa AA Sequence AQVGTNKELC CLVYTSWQIP QKFIVDYSET SPQCPKPGVI LLTKRGRQIC ADPNKKWVQK YISDLKLNA Biological Activity Full biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 1.0-10 ng/ml. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against 20 mM PB, pH 7.4, 100 mM NaCl. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human MIP-4/CCL18 (rHuMIP-4/CCL18) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA. Storage & Stability Lyophilized recombinant Human MIP-4/CCL18 (rHuMIP-4/CCL18) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background MIP-4/CCL18 is a CC chemokine ligand, acts as a neutral CCR3 antagonist, and is involved in inflammatory response. CCL18 is originally discovered as pulmonary and activation-regulated chemokine (PARC), dendritic cell (DC)-chemokine 1 (DC-CK1), alternative macrophage activation-associated CC chemokine-1 (AMAC-1), and macrophage inflammatory protein-4 (MIP-4). Enhanced CCL18 production has been demonstrated in several diseases, including various malignancies and inflammatory joint, lung, and skin diseases[1]. |
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