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Recombinant Human IFN-gamma Receptor II (CHO-expressed)
英文名:
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| 性狀 | Recombinant Human IFN-gamma Receptor II (CHO-expressed) 是干擾素 γ 受體的其中一個鏈,可以引起信號轉導的發生。
Synonyms rHuIFN-γ Receptor II; IFNGR2; IFNGT1 ; 重組人 IFN-γ 受體 II (CHO 細胞表達) Species Human Source CHO Accession P38484 Gene ID 3460 Molecular Weight 38-40 kDa AA Sequence SQLPAPQHPK IRLYNAEQVL SWEPVALSNS TRPVVYQVQF KYTDSKWFTA DIMSIGVNCT QITATECDFT AASPSAGFPM DFNVTLRLRA ELGALHSAWV TMPWFQHYRN VTVGPPENIE VTPGEGSLII RFSSPFDIAD TSTAFFCYYV HYWEKGGIQQ VKGPFRSNSI SLDNLKPSRV YCLQVQAQLL WNKSNIFRVG HLSNISCYET MADASTELQQ Biological Activity The ED50 is <0.1 μg/mL as measured by HT-29 (HTB-38) cells. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human IFN-gamma Receptor II (CHO-expressed) (rHuIFN-γ Receptor II) to 100 μg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Human IFN-gamma Receptor II (CHO-expressed) (rHuIFN-γ Receptor II) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background IFN-γR2 leads to the initiation of the signal transduction events: activation of Jakl and Jak2 receptor associated protein tyrosine kinases, phosphorylation of the IFN-γR1 intracellular domain on Tyr440 followed by phosphorylation and activation of Statlα, the latent transcriptional factor[1]. |
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