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Recombinant Human AG-2, His (HEK293-expressed)
英文名：
Cas號(hào)：
Cas號(hào)：
檢測(cè)信息查詢
| 貨號(hào) | 規(guī)格 | 貨期 | 庫(kù)存 | 價(jià)格 | 促銷價(jià) | 訂購(gòu) |
| 1308132986-10 μg | 0 | ￥3200 | ||||
| 1308132986-50 μg | 0 | ￥9800 |
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| 性狀 | Recombinant Human AG-2, His (HEK293-expressed) 是帶有 N 末端 His 標(biāo)簽的人重組 AG-2，在 HEK293 細(xì)胞中表達(dá)。
Synonyms rHuAG-2, His; HPC8; AGR2; AG2 ; 重組人 AG-2，His (HEK293 細(xì)胞表達(dá)) Species Human Source HEK 293 Accession O95994 Gene ID 10551 Molecular Weight Approximately 18.0 kDa AA Sequence RDTTVKPGAK KDTKDSRPKL PQTLSRGWGD QLIWTQTYEE ALYKSKTSNK PLMIIHHLDE CPHSQALKKV FAENKEIQKL AEQFVLLNLV YETTDKHLSP DGQYVPRIMF VDPSLTVRAD ITGRYSNRLY AYEPADTALL LDNMKKALKL LKTELHHHHH H Biological Activity Data is not available. Appearance Solution Formulation Supplied as a 0.2 μm filter solution of 20 mM Tris, 200 mM NaCl, 10% Glycerol, pH 8.0. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution N/A Storage & Stability Recombinant Human AG-2, His (HEK293-expressed) (rHuAG-2, His) is stored at -20°C. It is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Shipping with dry ice. Background AG-2 (Anterior gradient 2) is a human ortholog of the Xenopus laevis cement gland protein and a member of the protein disulfide isomerase (PDI) family. AG-2 is highly expressed and secreted in malignant cancer types, including breast carcinomas, pancreatic cancer, glioblastoma, prostate cancer and metastatic colorectal cancer. AGR2 is also a pro-oncogenic protein that stimulates EGFR ligand amphiregulin, regulate p53 signaling, and interact with the AAA+ protein Reptin. Overexpressed AG-2 stabilizes HIF-1α in tumor cells[1][2]. |
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