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AMPK alpha 1 Phospho (pS487) (PRKAA1)
英文名：Rabbit Monoclonal Antibody
Cas號(hào)：
Cas號(hào)：
檢測(cè)信息查詢
| 貨號(hào) | 規(guī)格 | 貨期 | 庫(kù)存 | 價(jià)格 | 促銷價(jià) | 訂購(gòu) |
| 1308113330-100ul | 現(xiàn)貨 | 0 | ￥0 |
| 別 名 | PRKAA1 antibody, AMPK antibody, AMPKa1 antibody, MGC33776 antibody, MGC57364 antibody, 5'-AMP-activated protein kinase catalytic subunit alpha-1 antibody, antibody |
| Cas號(hào) | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 產(chǎn)品參數(shù) | 【產(chǎn)品介紹】The 5-AMP-activated protein kinase (AMPK),
a member of the SNF1 (sucrose nonfermentor) kinase family (1) AMPK is a heterotrimeric protein comprising α (63 kDa), β (38 kDa) and γ (38 kDa) subunits. The alpha subunit is the catalytic subunit (which requires phosphorylation to be active) (2-3). Beta and gamma are noncatalytic subunits, although they have been found to interact with the active subunit in liver. AMPK regulates fatty acid and sterol synthesis by phosphorylation of acetyl-CoA as well as cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase (4). AMPK also appears to play a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Recommended Applications WB, ICC, IP Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 ICC: 1:100 - 250 IP: 1:10 - 100 Species Reactivity Human Products Data Western blot analysis on 293T cell lysates using anti-Phospho-AMPK alpha 1 (pS487) RabMAb (cat. #2802-1). Cells were either (A) untreated (B) treated with LP. Immunofluorescent staining of HeLa cells using Phospho-specific anti-AMPK RabMAb (cat. # 2802-1). Specificity A phospho specific peptide corresponding to residues surrounding Serine 487 of human AMPK alpha 1 was used as an immunogen. |
| 性狀 | 【反應(yīng)特異性】Human
【克隆 ID】EPR3051 【用途】WB , ICC , IP 【抗原分子量】63kDa |
| 貯存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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