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CD59
英文名：Rabbit Monoclonal Antibody
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檢測信息查詢
| 貨號 | 規(guī)格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308113432-100ul | 現(xiàn)貨 | 0 | ￥0 |
| 別 名 | CD59 antibody, 16.3A5 antibody, 1F5 antibody, EJ16 antibody, EJ30 antibody, EL32 antibody, FLJ38134 antibody, FLJ92039 antibody, G344 antibody, HRF-20 antibody, HRF20 antibody, MAC-IP antibody, MACIF antibody, MEM43 antibody, MGC2354 antibody, MIC11 antib |
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| 產(chǎn)品參數(shù) | 【產(chǎn)品介紹】CD59 is a cell surface glycoprotein
that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. CD59 also plays a role in signal transduction pathways in the activation of T cells. Mutations in this protein cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction (1). Recommended Applications WB, ICC, IP, FC Applications and Recommended Dilution Factors WB: 1:50,000 - 200,000 ICC: 1:250 - 500 IP: 1:100 - 500 FC: 1:10 - 100 Species Reactivity * Human *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) HUVEC, (B) BxPC-3, and (C) fetal brain lysates using anti-CD59 RabMAb (cat. #5516-1). Flow cytometric analysis of permeabilized HUVEC cells using anti-CD59 RabMAb (red) (catalog # 5516-1) or a rabbit IgG (negative) (green). Specificity A synthetic peptide corresponding to residues in human CD59 was used as an immunogen. |
| 性狀 | 【反應(yīng)特異性】Human
【克隆 ID】EPR6426 【用途】WB , ICC , FC , IP 【抗原分子量】18-20kDa |
| 貯存 | Storage Condition and Buffer Store at -20° C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt. |
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