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IRS-1 Antibody
英文名：IRS-1 Antibody
Cas號(hào)：
Cas號(hào)：
檢測(cè)信息查詢
| 貨號(hào) | 規(guī)格 | 貨期 | 庫(kù)存 | 價(jià)格 | 促銷價(jià) | 訂購(gòu) |
| 1308114460-100ul | 現(xiàn)貨 | 0 | ￥0 |
| 別 名 | IRS-1 |
| Cas號(hào) | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 產(chǎn)品參數(shù) | 【產(chǎn)品介紹】Insulin recept o r substrates (IRS), the
maj o r intracellular substrates of the insulin recept o r (IR), are adapt o r proteins that transduce signals from the IR to downstream effect o r s that are imp o r tant f o r the biological effect of insulin (1-2). After insulin stimulation, IRS proteins are rapidly phosph o r ylated on multiple tyrosine residues. Once phosph o r ylated, IRS proteins bind a n d activate Grb-2, SHP2 a n d the PI3-K p85 subunit (2-3). IRS-1 functions as one of the key regulat o r s of IR a n d the insulin-like growth fact o r -1 recept o r . Disruption of IRS-1 causes growth retardation a n d insulin resistance associated with hypertension, hypertriglyceridemia, a n d impaired endothelium-dependent vascular relaxation (4-5) WB: 1:1,000 IHC: 1:50-100 ICC: 1:250-500 IP: 1:50 A. Western blot analysis on Hela cell lysate using anti-IRS-1 RabMAb (cat. # 1692-1), dilution 1:1,000. B. Immunohistochemical analysis of paraffin-embedded human breast carcinoma using anti-IRS-1 RabMAb (cat. # 1692-1). |
| 性狀 | 【產(chǎn)品類型】Rabbit Monoclonal IgG
【反應(yīng)特異性】Human 【克隆 ID】EP263Y 【用途】WB , IHC , ICC , IP 【產(chǎn)品性狀】 【陽(yáng)性對(duì)照】 【產(chǎn)品濃度】 【細(xì)胞定位】 【抗原分子量】170 kDa |
| 貯存 |
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