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LAT Phospho (pY191)
英文名：LAT Phospho (pY191)
Cas號：
Cas號：
檢測信息查詢
| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308114486-100ul | 現貨 | 0 | ￥0 |
| 別 名 | 36 kDa phospho-tyrosine adapter protein, pp36, p36-38 |
| Cas號 | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 產品參數 | 【產品介紹】LAT (linker f o r activation of T-cells)
is involved in the T-cell antigen recept o r (TCR) signal transduction pathway, a n d may play an imp o r tant role downstream in activating protein tyrosine kinases (1). LAT is phosph o r ylated by ZAP-70/Syk protein tyrosine kinases leading to recruitment of multiple signaling molecules (2). It has been found that Tyr191 a n d Tyr171 are required f o r T-cell activation a n d Tyr132 is required f o r the activation of PLCgamma1 a n d Ras signaling pathways, respectively. Tyr226 a n d Tyr191 are required f o r Vav binding, whereas Tyr171 a n d Tyr132 are necessary f o r association a n d activation of phosphoinositide 3-kinase activity a n d PLCgamma1 (3). WB: 1:2,000 IHC: 1:50 ICC: 1:50 IP: 1:10 A. Western blot analysis on Jurkat cell lysate using anti-Phospho-LAT (pY191) RabMAb (cat. #1225-1); dilution 1:2,000. (1) Jurkat plus anti-CDC a n d (2) Jurkat negative control. B. Immunohistochemical analysis of paraffin-embedded human tonsils using anti-Phospho-LAT (pY191) RabMAb (cat. #1225-1). |
| 性狀 | 【產品類型】Rabbit Monoclonal IgG
【反應特異性】Human , Mouse , Rat 【克隆 ID】E225 【用途】WB , IHC , ICC , IP 【產品性狀】 【陽性對照】 【產品濃度】 【細胞定位】 【抗原分子量】36/38 kDa |
| 貯存 |
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