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LAT Rabbit Antibody
英文名：LAT Rabbit Antibody
Cas號(hào)：
Cas號(hào)：
檢測(cè)信息查詢
| 貨號(hào) | 規(guī)格 | 貨期 | 庫(kù)存 | 價(jià)格 | 促銷價(jià) | 訂購(gòu) |
| 1308114487-100ul | 現(xiàn)貨 | 0 | ￥0 |
| 別 名 | LAT antibody, LAT1 antibody, pp36 antibody, Linker for activation of T-cells family member 1 antibody, p36-38 antibody |
| Cas號(hào) | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 產(chǎn)品參數(shù) | 【產(chǎn)品介紹】LAT (linker f o r activation of T-cells)
is involved in the T-cell antigen recept o r (TCR) signal transduction pathway, a n d may play an imp o r tant role downstream in activating protein tyrosine kinases (1). LAT is phosph o r ylated by ZAP-70/Syk protein tyrosine kinases leading to recruitment of multiple signaling molecules (2). It has been found that Tyr191 a n d Tyr171 are required f o r T-cell activation a n d Tyr132 is required f o r the activation of PLCgamma1 a n d Ras signaling pathways, respectively. Tyr226 a n d Tyr191 are required f o r Vav binding, whereas Tyr171 a n d Tyr132 are necessary f o r association a n d activation of phosphoinositide 3-kinase activity a n d PLCgamma1 (3). WB: 1:500 IHC: 1:100 Flow Cytometry: 1:40 IP: 1:60 A. Western blot analysis on Jurkat cell lysate using anti-LAT RabMAb (catalog #1499-1), dilution 1:500. B. Immunohistochemical analysis of paraffin-embedded human lymph node using anti-LAT RabMAb (catalog #1499-1). |
| 性狀 | 【產(chǎn)品類型】Rabbit Monoclonal IgG
【反應(yīng)特異性】 【克隆 ID】Y109 【用途】WB , IHC , FC , IP 【產(chǎn)品性狀】 【陽(yáng)性對(duì)照】 【產(chǎn)品濃度】 【細(xì)胞定位】 【抗原分子量】36/38 kDa |
| 貯存 |
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