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Recombinant Human Leukemia Inhibitory Factor
英文名：
Cas號(hào)：
Cas號(hào)：
檢測(cè)信息查詢
| 貨號(hào) | 規(guī)格 | 貨期 | 庫(kù)存 | 價(jià)格 | 促銷價(jià) | 訂購(gòu) |
| 1308132571-10 μg | 0 | ￥27000 |
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| 性狀 | Recombinant Human Leukemia Inhibitory Factor是參與各種神經(jīng)和炎癥過(guò)程的淋巴因子，例如急性期反應(yīng)，組織損傷和感染。
Synonyms rHuLIF; Differentiation-stimulating Factor; D factor; MLPLI Species Human Source E. coli Accession P15018 Gene ID 3976 Molecular Weight Approximately 19.7 kDa AA Sequence SPLPITPVNA TCAIRHPCHN NLMNQIRSQL AQLNGSANAL FILYYTAQGE PFPNNLDKLC GPNVTDFPPF HANGTEKAKL VELYRIVVYL GTSLGNITRD QKILNPSALS LHSKLNATAD ILRGLLSNVL CRLCSKYHVG HVDVTYGPDT SGKDVFQKKK LGCQLLGKYK QIIAVLAQAF Biological Activity The ED50 is <0.2 ng/mL as measured by TF-I cells, corresponding to a specific activity of >5 × 106 units/mg. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Leukemia Inhibitory Factor (rHuLIF) to 100 μg/mL using ddH2O. Storage & Stability Lyophilized recombinant Human Leukemia Inhibitory Factor (rHuLIF) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Leukemia Inhibitory Factor has been shown to possess a remarkable variety of actions. It releases calcium from bone tissue, and is the differentiation inhibitory factor preventing spontaneous differentiation in normal embryonic stem cells[1]. Leukemia inhibitory factor (LIF) is a neuropoietic cytokine involved in both the neural and immune responses to injury. Its levels are increased in a variety of animal and human inflammatory conditions. Administration of Leukemia Inhibitory Factor can suppress inflammatory signs in some cases, for instance after intratracheal lipopolysaccharide-induced inflammation. Leukemia Inhibitory Factor also increases corticosterone levels via the hypothalamo-pituitary-adrenal axis. Other evidence suggests, that it can also act as a proinflammatory cytokine. Exogenously added Leukemia Inhibitory Factor induces acute phase protein expression and stimulates the production of proinflammatory cytokines and monocyte chemoattractants[2]. |
| 貯存 |
- 己二胺四甲叉膦酸六鉀鹽 38820-59-6
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