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Recombinant Human Noggin (CHO-expressed)
英文名：
Cas號(hào)：
Cas號(hào)：
檢測信息查詢
| 貨號(hào) | 規(guī)格 | 貨期 | 庫存 | 價(jià)格 | 促銷價(jià) | 訂購 |
| 1308132573-10 μg | 0 | ￥2400 | ||||
| 1308132573-50 μg | 0 | ￥9200 |
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| 性狀 | Recombinant Human Noggin (CHO-expressed) 是骨形態(tài)發(fā)生蛋白 (BMPs) 的拮抗劑，對(duì) hBMP-4 有很高的親和性，而對(duì) hBMP-7 的親和性較低，它在骨骼發(fā)展過程中是必不可少的。
Synonyms rHuNoggin; NOG ; 重組人頭蛋白 (CHO 細(xì)胞表達(dá)) Species Human Source CHO Accession Q13253 Gene ID 9241 Molecular Weight 29-31 kDa AA Sequence QHYLHIRPAP SDNLPLVDLI EHPDPIFDPK EKDLNETLLR SLLGGHYDPG FMATSPPEDR PGGGGGAAGG AEDLAELDQL LRQRPSGAMP SEIKGLEFSE GLAQGKKQRL SKKLRRKLQM WLWSQTFCPV LYAWNDLGSR FWPRYVKVGS CFSKRSCSVP EGMVCKPSKS VHLTVLRWRC QRRGGQRCGW IPIQYPIISE CKCSC Biological Activity The ED50 is <2.5 ng/mL as measured by ATDC5 cells. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Noggin (CHO-expressed) (rHuNoggin) to 100 μg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Human Noggin (CHO-expressed) (rHuNoggin) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Human Noggin protein has 205 amino acids (residues 28-232) after removal of its signal sequence (residues 1-27) and is secreted as a glycosylated, covalently linked homodimer, binds with high affinity to hBMP-4, and with lower affinity to hBMP-7 and acts as an antagonist of bone morphogenetic proteins (BMPs)[1]. Noggin is essential for proper skeletal development; excess BMP activity in the Noggin null mutant results in excess cartilage and failure to initiate joint formation[2]. |
| 貯存 |
- Recombinant Human Keratinocyte Growth Factor 1/FGF-7
- Recombinant Human Keratinocyte Growth Factor-2/FGF-10
- Recombinant Human Leukemia Inhibitory Factor
- Recombinant Human Macrophage Colony-stimulating Factor
- Recombinant Human Noggin (CHO-expressed)
- Recombinant Human Oncostatin-M, 227a.a.
- Recombinant Human Oncostatin-M, 209a.a.
- Recombinant Human Osteoprotegerin
- Recombinant Human Pigment Epithelium-derived Factor
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