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Recombinant Mouse Tumor Necrosis Factor-alpha/TNFSF2
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| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132615-10 μg | 0 | ¥2800 | ||||
| 1308132615-50 μg | 0 | ¥8800 |
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| 性狀 | Recombinant Mouse Tumor Necrosis Factor-alpha/TNFSF2 是一種很強的促炎性細胞因子,在免疫系統中具有調節功能,同時在炎癥,細胞增殖、分化及凋亡過程中發揮著重要作用。
Synonyms rMuTNF-α/TNFSF2; TNF-alpha; Cachectin; DIF; TNFA; Differentiation-inducing factor ; 重組小鼠腫瘤壞死因子-α/TNFSF2 Species Mouse Source E. coli Accession P06804 Gene ID 21926 Molecular Weight Approximately 17.3 kDa AA Sequence LRSSSQNSSD KPVAHVVANH QVEEQLEWLS QRANALLANG MDLKDNQLVV PADGLYLVYS QVLFKGQGCP DYVLLTHTVS RFAISYQEKV NLLSAVKSPC PKDTPEGAEL KPWYEPIYLG GVFQLEKGDQ LSAEVNLPKY LDFAESGQVY FGVIAL Biological Activity The ED50 is <0.05 ng/mL as measured by murine L929 cells, corresponding to a specific activity of >2.0 × 107 units/mg. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Murine Tumor Necrosis Factor-alpha/TNFSF2 (rMuTNF-α/TNFSF2) to 100 μg/mL using ddH2O or PBS. Storage & Stability Lyophilized recombinant Murine Tumor Necrosis Factor-alpha/TNFSF2 (rMuTNF-α/TNFSF2) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Tumor necrosis factor α (TNF-α, also known as cachectin) is a strong pro-inflammatory cytokine playing an important role in the immune system during inflammation, cell proliferation, differentiation and apoptosis. TNF-α is type II transmembrane protein that can be expressed in both membrane-bound and secreted forms. Receptors for TNF-a are part of TNF receptor (TNFR) superfamily, with characteristic intracellular segment, a transmembrane domain, and an extracellular ligand-binding domain. They are type I transmembrane glycoproteins characterized by a cysteinerich motif (up to 40 aminoacids) repeated 2-6 times in the extracellular N-terminal domain[1]. |
| 貯存 |
- Recombinant Mouse Macrophage Colony Stimulating Factor
- Recombinant Mouse Noggin (CHO-expressed)
- Recombinant Mouse Platelet-derived Growth Factor-BB
- Recombinant Mouse Thrombopoietin (CHO-expressed)
- Recombinant Mouse Tumor Necrosis Factor-alpha/TNFSF2
- Recombinant Rat Basic Fibroblast Growth Factor
- Recombinant Rat Epidermal Growth Factor
- Recombinant Rat Granulocyte-Macrophage Colony Stimulating Factor (CHO-expressed)
- Recombinant Rat Interferon-gamma
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