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Recombinant Rat Basic Fibroblast Growth Factor
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檢測信息查詢
| 貨號 | 規(guī)格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132616-10 μg | 0 | ￥2400 | ||||
| 1308132616-50 μg | 0 | ￥4400 |
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| 性狀 | Recombinant Rat Basic Fibroblast Growth Factor 是由 FGF2 基因編碼的生長因子和信號傳導蛋白。
Synonyms rRtbFGF; HBGF-2; FGF-2; FGF-b; FGF-basic Species Rat Source E. coli Accession P13109 Gene ID 54250 Molecular Weight Approximately 16.4 kDa AA Sequence GPALPEDGGG AFPPGHFKDP KRLYCKNGGF FLRIHPDGRV DGVREKSDPH VKLQLQAEER GVVSIKGVCA NRYLAMKEDG RLLASKCVTE ECFFFERLES NNYNTYRSRK YSSWYVALKR TGQYKLGSKT GPGQKAILFL PMSAKS Biological Activity The ED50 is <0.25 ng/mL as measured by 3T3 cells, corresponding to a specific activity of > 4.0 × 106 units/mg. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Rat Basic Fibroblast Growth Factor (rRtbFGF) to 100 μg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Rat Basic Fibroblast Growth Factor (rRtbFGF) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Recombinant Rat Basic Fibroblast Growth Factor is a potent mitogen and chemoattractant for endothelial cells as well as fibroblasts. Basic fibroblast growth factor (bFGF) is a heparin-binding mitogen for mesoderm-derived cells, also acts as a mitogen, differentiation inducing and maintenance factor for many neuroectodermal cells including glial cells, neurons, paraneurons, and their tumor counterparts. The molecule is expressed in several types of neuroectodermal cells. bFGF occurs in many neuronal target tissues, and can prevent ontogenetic as well as lesion-induced neuron death[1]. In vitro, basic fibroblast growth factor induces an angiogenic phenotype in endothelial cells, which includes chemotaxis, mitogenesis, protease production, beta-integrin expression, and tube formation in three-dimensional gels. It acts by binding to specific tyrosine kinase receptors and to cell-associated heparan sulfate proteoglycans[2]. |
| 貯存 |
- Recombinant Mouse Noggin (CHO-expressed)
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- Recombinant Mouse Thrombopoietin (CHO-expressed)
- Recombinant Mouse Tumor Necrosis Factor-alpha/TNFSF2
- Recombinant Rat Basic Fibroblast Growth Factor
- Recombinant Rat Epidermal Growth Factor
- Recombinant Rat Granulocyte-Macrophage Colony Stimulating Factor (CHO-expressed)
- Recombinant Rat Interferon-gamma
- Recombinant Rat Interleukin-1 alpha (CHO-expressed)
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