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Recombinant Human Transforming Growth Factor β2
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檢測信息查詢
| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132639-2 μg | 0 | ￥3700 | ||||
| 1308132639-10 μg | 0 | ￥5800 |
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| 性狀 | Recombinant Human Transforming Growth Factor β2是一種多功能細胞因子，參與控制細胞生長和分化，誘導纖維化，引起免疫應答的抑制，并在胚胎發育過程中起著至關重要的作用。
Synonyms TGF-beta-2; Cetermin; G-TSF; TGFB2; Polyergin; rHuTGF-β2 Species Human Source HEK 293 Accession P61812 Gene ID 7042 Molecular Weight Approximately 12.7 kDa AA Sequence ALDAAYCFRN VQDNCCLRPL YIDFKRDLGW KWIHEPKGYN ANFCAGACPY LWSSDTQHSR VLSLYNTINP EASASPCCVS QDLEPLTILY YIGKTPKIEQ LSNMIVKSCK CS Biological Activity The ED50 is <0.2 ng/mL as measured by mouse HT-2 cells. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against 4 mM HCl. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Transforming Growth Factor β2 (rHuTGF-β2) to 100 μg/mL using ddH2O. Storage & Stability Lyophilized recombinant Human Transforming Growth Factor β2 (rHuTGF-β2) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background TGFβ is released from degranulating platelets and secreted by all of the major cell types participating in the repair process, including lymphocytes, macrophages, endothelial cells, smooth muscle cells, epithelial cells, and fibroblasts. Mammals express three isoforms of TGFβ designated TGFβI, TGFβ2, and TGFβ3; TGFβ1 is the most abundant isoform in all tissues, and in human platelets it is the only isoform of the peptide. Certain cells such as retinal pigment epithelial cells secrete predominantly TGFβ2, and certain body fluids such as the aqueous and vitreous of the eye, amniotic fluid, saliva, and breast milk contain principally TGFβ2. TGFβ3 is the least studied of the TGFβ isoforms. It has been isolated from human umbilical cord and is secreted from certain cells, including myoblast celllines; however, it is usually less abundant than either TGFβ1 or TGFβ2 in both tissue and cell extracts[1]. Transforming Growth Factor β2 mediates various cell-cell interactions that occur during embryonic development. It is previously shown that Transforming Growth Factor β2 mRNA is expressed at chondrogenic sites in the developing limb. When Transforming Growth Factor β2-soaked beads are implanted in the limb bud, extra digits are induced, and mice lacking Transforming Growth Factor β2 has minor skeletal defects in the limb[2]. |
| 貯存 |
- Recombinant Human R-spondin-1/RSPO1
- Recombinant Human BDNF/Brain-derived neurotrophic factor
- Recombinant Mouse TGF-beta 1/TGFB1 (HEK293-expressed)
- Recombinant Human Transforming Growth Factor β1
- Recombinant Human Transforming Growth Factor β2
- Recombinant Human Transforming Growth Factor beta3 (HEK293-expressed)
- Recombinant Human Hepatocyte Growth Factor (CHO-expressed)
- Recombinant Human Fibroblast Growth Factor 18
- Recombinant Rat Fibroblast Growth Factor 18
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