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Recombinant Human BDNF/Brain-derived neurotrophic factor
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檢測信息查詢
| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132636-10 μg | 0 | ￥4400 | ||||
| 1308132636-50 μg | 0 | ￥14800 |
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| 性狀 | Recombinant Human BDNF/Brain-derived neurotrophic factor (E.coli) 是一種神經營養因子，能夠與 TrkB 受體結合，調節神經發育過程，包括神經元的存活，分化，及突觸可塑性。
Synonyms rHuBDNF/Brain-derived neurotrophic factor; Abrineurin ; 重組人腦源性神經營養因子 (E.coli 表達) Species Human Source E. coli Accession P23560 Gene ID 627 Molecular Weight Approximately 13 kDa AA Sequence HSDPARRGEL SVCDSISEWV TAADKKTAVD MSGGTVTVLE KVPVSKGQLK QYFYETKCNP MGYTKEGCRG IDKRHWNSQC RTTQSYVRAL TMDSKKRIGW RFIRIDTSCV CTLTIKRGR Biological Activity The ED50 is <5 μg/ml measured by its ability to bind Human TrkB in functional ELISA. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against 20 mM PB, 250 mM NaCl, pH 7.2. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human BDNF/Brain-derived neurotrophic factor (rHuBDNF/Brain-derived neurotrophic factor) to 100 μg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Human BDNF/Brain-derived neurotrophic factor (rHuBDNF/Brain-derived neurotrophic factor) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Recombinant Human BDNF/Brain-derived neurotrophic factor is a neurotrophin binding to the high-affinity tropomyosin-related receptor kinase B (TrkB) receptor to regulate neurodevelopmental processes, including neuronal survival, neuronal differentiation, and synaptic plasticity[1]. Brain-derived neurotrophic factor (BDNF) is one of the most abundant neurotrophins in the mammalian central nervous system that promotes neuronal survival and differentiation. BDNF plays crucial roles in the cardiovascular system[2]. |
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