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Recombinant Human Glial Cell Line-derived Neurotrophic Factor
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檢測信息查詢
| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132700-10 μg | 0 | ￥4200 | ||||
| 1308132700-50 μg | 0 | ￥14400 |
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| 性狀 | Recombinant Human Glial Cell Line-derived Neurotrophic Factor 是一種能有效促進多種神經元存活的小蛋白。
Synonyms rHuGDNF; ATF ; 重組人膠質細胞源性神經營養因子 Species Human Source E. coli Accession P39905 Gene ID 2668 Molecular Weight Approximately 17 kDa AA Sequence MSPDKQMAVL PRRERNRQAA AANPENSRGK GRRGQRGKNR GCVLTAIHLN VTDLGLGYET KEELIFRYCS GSCDAAETTY DKILKNLSRN RRLVSDKVGQ ACCRPIAFDD DLSFLDDNLV YHILRKHSAK RCGCI Biological Activity The ED50 is <5 μg/mL as measured by C6 cells. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Glial Cell Line-derived Neurotrophic Factor (rHuGDNF) to 100 μg/mL using ddH2O or PBS. Storage & Stability Lyophilized recombinant Human Glial Cell Line-derived Neurotrophic Factor (rHuGDNF) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Glial Cell Line-derived Neurotrophic Factor (GDNF) is a small protein that potently promotes the survival of many types of neurons[1]. GDNF is a neurotrophic factor that is a member of the TGF-β superfamily. GDNF is a glycosylated disulfide-linked homodimeric protein of approximately 15 kDa. GDNF promotes survival of various neuronal cells in central and peripheral nervous systems and different stages of development, including motoneurons, midbrain dopaminergic neurons, Purkinje cells and sympathetic neurons. Cells known to express GDNF include Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes and skeletal muscle cells[1][2]. |
| 貯存 |
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