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Recombinant Mouse Granzyme B (CHO-expressed)
英文名：
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檢測信息查詢
| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132703-10 μg | 0 | ￥4200 | ||||
| 1308132703-50 μg | 0 | ￥12400 |
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| 性狀 | Recombinant Mouse Granzyme B (CHO-expressed) 在細胞凋亡中發揮重要作用，通過刺激細胞因子釋放參與炎癥誘導，并參與細胞外基質重構。
Synonyms rMuGranzyme B; CTLA-1; CCP1; Fragmentin-2; Gzmb ; 重組小鼠顆粒酶 B (CHO 細胞表達) Species Mouse Source CHO Accession P04187 Gene ID 14939 Molecular Weight Approximately 32 kDa AA Sequence IIGGHEVKPH SRPYMALLSI KDQQPEAICG GFLIREDFVL TAAHCEGSII NVTLGAHNIK EQEKTQQVIP MVKCIPHPDY NPKTFSNDIM LLKLKSKAKR TRAVRPLNLP RRNVNVKPGD VCYVAGWGRM APMGKYSNTL QEVELTVQKD RECESYFKNR YNKTNQICAG DPKTKRASFR GDSGGPLVCK KVAAGIVSYG YKDGSPPRAF TKVSSFLSWI KKTMKSS Biological Activity The specific activity is >1000 nM/min per μg of enzyme, measured by its ability to cleave a chromogenic peptide substrate (Ac-IEPD-pNA). Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Mouse Granzyme B (CHO-expressed) (rMuGranzyme B) to 100 μg/mL using ddH2O or PBS. Storage & Stability Lyophilized recombinant Mouse Granzyme B (CHO-expressed) (rMuGranzyme B) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Granzyme B plays essential roles in mammalian apoptosis[1]. Granzyme B is a serine protease most commonly found in the granules of cytotoxic lymphocytes (CTLs), natural killer cells (NK cells) and cytotoxic T cells. It is secreted by these cells along with the pore forming protein perforin to mediate apoptosis in target cells. Granzyme B has shown to be involved in inducing inflammation by stimulating cytokine release and is also involved in extracellular matrix remodeling[2]. |
| 貯存 |
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- Recombinant Mouse Granzyme B (CHO-expressed)
- Recombinant Mouse GRO alpha/CXCL1 (CHO-expressed)
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- Recombinant Human GRO beta/CXCL2
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