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Recombinant Human Hemofiltrate CC Chemokine-1/CCL14
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檢測信息查詢
| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132712-10 μg | 0 | ￥3800 | ||||
| 1308132712-50 μg | 0 | ￥8400 |
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| 性狀 | Recombinant Human Hemofiltrate CC Chemokine-1/CCL14 對人的單核細胞有較弱的活性，通過受體發揮作用，也能識別MIP-1 alpha。
Synonyms rHuHCC-1/CCL14; C-C motif chemokine 14; SCYA14 ; 重組人 CC 趨化因子14 Species Human Source E. coli Accession Q16627 Gene ID 6358 Molecular Weight Approximately 8.4 kDa AA Sequence TESSSRGPYH PSECCFTYTT YKIPRQRIMD YYETNSQCSK PGIVFITKRG HSVCTNPSDK WVQDYIKDMK EN Biological Activity The ED50 is <25 μg/mL as measured by CHO cells transfected with human CCR5, corresponding to a specific activity of >40 units/mg. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Hemofiltrate CC Chemokine-1/CCL14 (rHuHCC-1/CCL14) to 100 μg/mL using ddH2O. Storage & Stability Lyophilized recombinant Human Hemofiltrate CC Chemokine-1/CCL14 (rHuHCC-1/CCL14) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Human Hemofiltrate CC Chemokine-1/CCL14 (HCC-1) is expressed constitutively in several normal tissues (spleen, liver, skeletal and heart muscle, gut, and bone marrow), and is present at high concentrations (1-80 nM) in plasma. HCC-1 has weak activities on human monocytes and acts via receptors that also recognize MIP-lot. It induces intracellular Ca2+ changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and is inactive on T lymphocytes, neutrophils, and eosinophil leukocytes. In addition, HCC-1 enhances the proliferation of CD34+ myeloid progenitor cells. It is as effective as MIP-1α, but about 100-fold less potent[1]. CCL14 regulate extracellular matrix and adhesion molecules in the trophoblast[2]. |
| 貯存 |
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- Recombinant Human Hemofiltrate CC Chemokine-1/CCL14
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- Recombinant Human I-309/CCL1
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