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Recombinant Human I-309/CCL1
英文名：
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檢測信息查詢
| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132714-10 μg | 0 | ￥3800 | ||||
| 1308132714-50 μg | 0 | ￥9800 |
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| 性狀 | Recombinant Human I-309/CCL1 通過與細胞表面的CCR8趨化因子受體相互作用，吸引單核細胞、自然殺傷細胞、未成熟的B細胞核樹突狀細胞。
Synonyms rHuI-309/CCL1; C-C motif chemokine 1; SCYA1 ; 重組人I-309/CCL1 Species Human Source E. coli Accession P22362 Gene ID 6346 Molecular Weight Approximately 8.5 kDa AA Sequence SKSMQVPFSR CCFSFAEQEI PLRAILCYRN TSSICSNEGL IFKLKRGKEA CALDTVGWVQ RHRKMLRHCP SKRK Biological Activity The ED50 is <1 μg/mL as measured by CHO-K1/Gα15/hCCR8 cells (human Gα15 and human CCR8 stably expressed in CHO-K1 cells). Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human I-309/CCL1 (rHuI-309/CCL1) to 100 μg/mL using ddH2O or PBS. Storage & Stability Lyophilized recombinant Human I-309/CCL1 (rHuI-309/CCL1) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Human I-309/CCL1 is a monocytec hemoattractant[1]. CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with a cell surface chemokine receptor called CCR8. The CC chemokine I-309 is the only agonist that selectively induced intracellular Ca2+ mobilization and chemotaxis in receptor-transfected 300-19 cells. TER1 (ChemR1 or CKR-L1) is the receptor for I-309, and we propose to call this receptor CCR8 in agreement with the current nomenclature for chemokine receptors[2]. |
| 貯存 |
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- Recombinant Human I-309/CCL1
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