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Recombinant Rat Interleukin-18
英文名:
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| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132723-10 μg | 0 | ¥3800 | ||||
| 1308132723-50 μg | 0 | ¥11400 |
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| 性狀 | Recombinant Rat Interleukin-18 具有免疫調節活性,包括協助Th1細胞和自然殺傷細胞刺激IFN-γ的生成,以及其它促進炎癥的活動。
Synonyms rRtIL-18; Interferon-gamma-inducing factor; IL-1 gamma ; 重組大鼠白細胞介素-18 Species Rat Source E. coli Accession P97636 Gene ID 29197 Molecular Weight Approximately 18.4 kDa AA Sequence MHFGRLHCTT AVIRSINDQV LFVDKRNPPV FEDMPDIDRT ANESQTRLII YMYKDSEVRG LAVTLSVKDG RMSTLSCKNK IISFEEMNPP ENIDDIKSDL IFFQKRVPGH NKMEFESSLY EGHFLACQKE DDAFKLVLKR KDENGDKSVM FTLTNLHQS Biological Activity The ED50 is <2 μg/mL as measured by KG-1 cells, corresponding to a specific activity of >500 units/mg. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against 50 mM Tris, 50 mM NaCl, pH 8.0. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Rat Interleukin-18 (rRtIL-18) to 100 μg/mL using ddH2O. Storage & Stability Lyophilized recombinant Rat Interleukin-18 (rRtIL-18) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Interleukin (IL)-18 is a potent stimulator of immunity and augments the severity of type II collagen-induced arthritis (CIA) in rats and mice by enhancing T helper 1 (Th1) cell activation, which increases the production of proinflammatory cytokines and arthritogenic antibodies. IL-18 possesses immunoregulatory activities, including the stimulation of interferon (IFN)-g production by T helper 1 (Th1) and natural killer cells, as well as other activities that promote inflammation[1]. |
| 貯存 |
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