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Recombinant Mouse MCP-1/CCL2 (HEK293-expressed)
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| 貨號 | 規(guī)格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132747-10 μg | 0 | ¥3900 | ||||
| 1308132747-50 μg | 0 | ¥10400 |
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| 性狀 | Recombinant Mouse MCP-1/CCL2 (HEK293-expressed) 是屬于CC趨化因子家族的細胞因子。
Synonyms rMuMCP-1/CCL2; C-C motif chemokine 2; MCAF; MCP-1; SCYA2 ; 重組小鼠MCP-1/CCL2 (HEK293-表達) Species Mouse Source HEK 293 Accession P10148 Gene ID 20296 Molecular Weight Approximately 8 kDa AA Sequence QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMR Biological Activity The ED50 is <0.3 μg/mL as measured by CHO-K1/Gα15/mCCR2 cells (human Gα15 and mouse CCR2 stably expressed in CHO-K1 cells). Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Mouse MCP-1/CCL2 (HEK293-expressed) (rMuMCP-1/CCL2) to 100 μg/mL using ddH2O or PBS. Storage & Stability Lyophilized recombinant Mouse MCP-1/CCL2 (HEK293-expressed) (rMuMCP-1/CCL2) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background CCL2 is produced by a variety of cell types, either constitutively or after induction by oxidative stress, cytokines, or growth factors. CCL2 is produced by many cell types, including endothelial, fibroblasts, epithelial, smooth muscle, mesangial, astrocytic, monocytic, and microglial cells. CCL2 regulates the migration and infiltration of monocytes, memory T lymphocytes, and natural killer (NK) cells[1]. The chemokine CCL2 and its main chemokine receptor CCR2 have been implicated in the pathogenesis of several different disease processes, including vascular permeability and attraction of immune cells during metastasis, a number of different neurological disorders, autoimmune disease, obesity, and atherosclerosis[2]. |
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