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Recombinant Human PDGF-DD (CHO-expressed)
英文名:
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| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132791-10 μg | 0 | ¥3200 | ||||
| 1308132791-50 μg | 0 | ¥9800 |
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| 性狀 | Recombinant Human PDGF-DD (CHO-expressed) 屬于 PDGF 家族,能夠特異性地結合并激活其同源受體 PDGFR-β,通過激活多個下游致癌途徑參與調節腫瘤增殖、轉化和侵襲,導致腫瘤發展。
Synonyms rHuPDGF-DD; Platelet-derived growth factor D; SCDGFB ; 重組人血小板衍生生長因子-DD (CHO 細胞表達) Species Human Source CHO Accession Q9GZP0 Gene ID 80310 Molecular Weight 19-21 kDa AA Sequence SYHDRKSKVD LDRLNDDAKR YSCTPRNYSV NIREELKLAN VVFFPRCLLV QRCGGNCGCG TVNWRSCTCN SGKTVKKYHE VLQFEPGHIK RRGRAKTMAL VDIQLDHHER CDCICSSRPP R Biological Activity The ED50 is <5 μg/mL as measured by 3T3 cells. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human PDGF-DD (CHO-expressed) (rHuPDGF-DD) to 100 μg/mL using ddH2O or PBS. Storage & Stability Lyophilized recombinant Human PDGF-DD (CHO-expressed) (rHuPDGF-DD) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background PDGF-DD is a member of the PDGF family, specifically binds to and activates its cognate receptor PDGFR-β, and participates in regulating cancer proliferation, transformation, and invasion through activating multiple downstream oncogenic pathways, resulting in tumor development and progression[1]. |
| 貯存 |
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