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Recombinant Human VEGF-C (HEK293-expressed)
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| 貨號 | 規(guī)格 | 貨期 | 庫存 | 價(jià)格 | 促銷價(jià) | 訂購 |
| 1308132823-10 μg | 0 | ￥3800 | ||||
| 1308132823-50 μg | 0 | ￥10800 |
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| 性狀 | Recombinant Human VEGF-C (HEK293-expressed) 在淋巴管的生成過程中發(fā)揮作用，主要通過其受體VEGFR-3作用于淋巴管內(nèi)皮細(xì)胞，促進(jìn)其生存、生長和遷移。
Synonyms rHuVEGF-C; Vascular endothelial growth factor C; Flt4-L; VRP ; 重組人源血管內(nèi)皮生長因子C (HEK293細(xì)胞表達(dá)) Species Human Source HEK 293 Accession P49767 Gene ID 7424 Molecular Weight 16-19 kDa AA Sequence MAHYNTEILK SIDNEWRKTQ CMPREVCIDV GKEFGVATNT FFKPPCVSVY RCGGCCNSEG LQCMNTSTSY LSKTLFEITV PLSQGPKPVT ISFANHTSCR CMSKLDVYRQ VHSIIRR Biological Activity The ED50 is <0.5 μg/mL as measured by HMVEC human microvascular endothelial cells. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human VEGF-C (HEK293-expressed) (rHuVEGF-C) to 100 μg/mL using ddH2O or PBS. Storage & Stability Lyophilized recombinant Human VEGF-C (HEK293-expressed) (rHuVEGF-C) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background The main function of VEGF-C is in lymphangiogenesis, where it acts on lymphatic endothelial cells (LECs) primarily via its receptor VEGFR-3 promoting survival, growth and migration[1]. However, in addition to its effect on lymphatic vessels, it can also promote the growth of blood vessels and regulate their permeability. The effect on blood vessels can be mediated via its primary receptor VEGFR-3 or its secondary receptor VEGFR-2[2]. Apart from vascular targets, VEGF-C is also important for neural development and blood pressure regulation[3][4]. |
| 貯存 |
- Recombinant Human Tyrosine kinase receptor A (HEK293-expressed)
- Recombinant Human TWEAK (CHO-expressed)
- Recombinant Rat VEGF164 (P.pastoris-expressed)
- Recombinant Rat VEGF165 (CHO-expressed)
- Recombinant Human VEGF-C (HEK293-expressed)
- Recombinant Human VEGF-D (HEK293-expressed)
- Recombinant Human WISP-1 (CHO-expressed)
- Recombinant Human Epidermal Growth Factor Receptor, His (Sf9 insect cells-expressed)
- Recombinant Human 4-1BB, Fc Chimera (CHO-expressed)
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