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Recombinant Human Betacellulin (HEK293-expressed)
英文名：
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Cas號(hào)：
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| 貨號(hào) | 規(guī)格 | 貨期 | 庫存 | 價(jià)格 | 促銷價(jià) | 訂購 |
| 1308132841-10 μg | 0 | ￥3200 | ||||
| 1308132841-50 μg | 0 | ￥8400 |
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| 性狀 | Recombinant Human Betacellulin (HEK293-expressed) 是 HEK293 細(xì)胞中產(chǎn)生的一種糖蛋白，能夠通過提高來自導(dǎo)管和胰腺腺泡細(xì)胞的 β 細(xì)胞的分化和再生來提高葡萄糖耐受性。
Synonyms rHuBetacellulin; BTC Species Human Source HEK 293 Accession P35070 Gene ID 685 Molecular Weight 15-18 kDa AA Sequence DGNSTRSPET NGLLCGDPEE NCAATTTQSK RKGHFSRCPK QYKHYCIKGR CRFVVAEQTP SCVCDEGYIG ARCERVDLFY Biological Activity The ED50 is <4 pg/mL as measured by 3T3 cells. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Betacellulin (HEK293-expressed) (rHuBetacellulin) to 100 μg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Human Betacellulin (HEK293-expressed) (rHuBetacellulin) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Betacellulin (BTC), a member of the epidermal growth factor family, is expressed predominantly in the human pancreas and induces the differentiation of a pancreatic acinar cell line (AR42J) into insulin-secreting cells. Betacellulin binds and activates the EGF receptor (EGFR/erbB-1) and erbB-4, and it induces tyrosine phosphorylation of erbB-2, which couples with the EGFR or erbB-4[1]. |
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