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Recombinant Mouse Betacellulin
英文名：
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檢測信息查詢
| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132842-10 μg | 0 | ￥3800 | ||||
| 1308132842-50 μg | 0 | ￥9800 |
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| 性狀 | Recombinant Mouse Betacellulin 是 E. coli 產生的表皮生長因子家族的一員，可誘導胰腺 β 細胞的分化，促進 β 細胞的再生。
Synonyms rMuBetacellulin; BTC Species Mouse Source E. coli Accession Q05928 Gene ID 12223 Molecular Weight Approximately 9.2 kDa AA Sequence MDGNTTRTPE TNGSLCGAPG ENCTGTTPRQ KVKTHFSRCP KQYKHYCIHG RCRFVVDEQT PSCICEKGYF GARCERVDLF Y Biological Activity The ED50 is <0.5 ng/mL as measured by 3T3 cells, corresponding to a specific activity of >2 × 106 units/mg. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against 50 mM Tris, 300 mM NaCl, pH 9.0. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Mouse Betacellulin (rMuBetacellulin) to 100 μg/mL using ddH2O. Storage & Stability Lyophilized recombinant Mouse Betacellulin (rMuBetacellulin) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Betacellulin (BTC), a member of the epidermal growth factor (EGF) family, induces differentiation of pancreatic β-cells and promotes regeneration of β-cells in experimental diabetes. BTC stimulates DNA synthesis in fibroblasts and vascular smooth muscle cells. BTC plays a role in regulating growth and/or differentiation of endocrine precursor cells of the fetal pancreas. BTC is found to convert amylase-secreting pancreatic AR42J cells into insulin-producing cells and to have a mitogenic effect in human undifferentiated pancreatic epithelial cells[1]. |
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