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EGFR (C-term)
英文名：Rabbit Monoclonal IgG
Cas號：
Cas號：
檢測信息查詢
| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308113539-100ul | 現貨 | 0 | ￥0 |
| 別 名 | Recept o r tyrosine-protein kinase ErbB-1 |
| Cas號 | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 產品參數 | 【產品介紹】Epidermal growth fact o r recept o r (EGFR) is
a 170 kDa transmembrane glycoprotein recept o r tyrosine kinase that, activated by epidermal growth fact o r (EGF), affects cell growth a n d differentiation (1). Binding of EGF o r TGF alpha to EGFR activates tyrosine kinase activity of the recept o r (2). The carboxy terminal tyrosine residues on EGFR, Tyr 1068, Tyr 1148, a n d Tyr 1173, are the maj o r sites of autophosph o r ylation, which occurs as a result of EGF binding (3). Once activated, EGFR phosphotyrosines Y-1068 a n d Y-1173 mediate the binding of Grb2 to the EGFR. Another autophosph o r ylation site, Tyr 1086, is situated within the cytoplasmic domain, a n d is phosph o r ylated to a higher extent by c-Src than by EGFR (4). WB: 1:10,000 ICC: 1:50 Flow Cytometry: 1:10 IP: 1:30 A. Western blot analysis on A431 cell lysate using anti-EGFR (C-term) RabMAb (cat. #2235-1); dilution 1:10,000. B. Immunoflu o r escent staining of A431 cells using anti-EGFR (C-term) RabMAb (cat. #2235-1). |
| 性狀 | 【反應特異性】Human
【克隆 ID】E235 【用途】WB , ICC , FC , IP 【抗原分子量】170 kDa |
| 貯存 |
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