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HTR2C
英文名：HTR2C
Cas號：
Cas號：
檢測信息查詢
| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308114421-100ul | 現貨 | 0 | ￥0 |
| 別 名 | HTR2C antibody, 5-HT2C antibody, 5-HTR2C antibody, HTR1C antibody, 5-hydroxytryptamine receptor 2C antibody, Serotonin receptor 2C antibody |
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| 產品參數 | 【產品介紹】Serotonin (5-hydroxytryptamine, 5-HT),
a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. HTR2C is the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines. RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in patterns of HTR2C editing in depressed suicide victims (1). Recommended Applications WB Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 Species Reactivity * Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) SH-SY5Y, (B) BxPC-3, (C) Molt-4, (D) mouse kidney, and (E) rat kidney lysates using anti-HTR2C RabMAb (cat. #5315-1). Specificity A synthetic peptide corresponding to residues near the C-terminus of human HTR2C was used as an immunogen. |
| 性狀 | 【產品類型】Rabbit Monoclonal Antibody
【反應特異性】Human , Mouse , Rat 【克隆 ID】EPR6487 【用途】WB 【產品性狀】 【陽性對照】 【產品濃度】 【細胞定位】 【抗原分子量】63kDa |
| 貯存 | Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
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