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Recombinant Human CD47, His (HEK293-expressed)
英文名：
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檢測信息查詢
| 貨號 | 規(guī)格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132849-10 μg | 0 | ￥2400 | ||||
| 1308132849-50 μg | 0 | ￥6400 |
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| 性狀 | Recombinant Human CD47, His (HEK293-expressed) 是在 HEK293 中產(chǎn)生的帶有 His 標(biāo)簽的多肽鏈。CD47 是癌癥免疫療法的重要靶標(biāo)。
Synonyms rHuCD47, His; CD47; MER6; IAP; OA3 Species Human Source HEK 293 Accession Q08722 Gene ID 961 Molecular Weight 35-40 kDa AA Sequence QLLFNKTKSV EFTFCNDTVV IPCFVTNMEA QNTTEVYVKW KFKGRDIYTF DGALNKSTVP TDFSSAKIEV SQLLKGDASL KMDKSDAVSH TGNYTCEVTE LTREGETIIE LKYRVVSWFS PHHHHHH Biological Activity 2 μg/mL (100 μL/well) of immoblized recombinant human CD47-His can bind human SIRPa-Fc with a linear range of 20-65 ng/mL. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human CD47, His (HEK293-expressed) (rHuCD47, His) to 100 μg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Human CD47, His (HEK293-expressed) (rHuCD47, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Targeting CD47 is in the spotlight of cancer immunotherapy. Blocking CD47 triggers the recognition and elimination of cancer cells by the innate immunity. The CD47/SIRP-α axis has been established as an important regulator of innate anti-cancer immunity, with many if not all malignancies overexpressing the receptor CD47 that binds to phagocyte-expressed SIRP-α[1]. |
| 貯存 |
- Recombinant Human Bone Morphogenetic Protein-3B
- Recombinant Human CD19, Fc Chimera (CHO-expressed)
- Recombinant Human CD28, Fc Chimera (HEK293-expressed)
- Recombinant Human CD47, Fc Chimera (HEK293-expressed)
- Recombinant Human CD47, His (HEK293-expressed)
- Recombinant Mouse DCIP-1/CXCL3 (CHO-expressed)
- Recombinant Human Desert Hedgehog
- Recombinant Mouse Desert Hedgehog
- Recombinant Human EGF Receptor, His (CHO-expressed)
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