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Recombinant Rat Interleukin-6 (HEK293-expressed)
英文名：
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| 性狀 | Recombinant Rat Interleukin-6 (HEK293-expressed) 是一種 HEK293 細(xì)胞來(lái)源的多功能細(xì)胞因子，可調(diào)節(jié)各種免疫和炎癥反應(yīng)
Synonyms rRtIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2 Species Rat Source HEK 293 Accession P20607 Gene ID 24498 Molecular Weight 21-26 kDa AA Sequence FPTSQVRRGD FTEDTTHNRP VYTTSQVGGL ITYVLREILE MRKELCNGNS DCMNSDDALS ENNLKLPEIQ RNDGCFQTGY NQEICLLKIC SGLLEFRFYL EFVKNNLQDN KKDKARVIQS NTETLVHIFK QEIKDSYKIV LPTPTSNALL MEKLESQKEW LRTKTIQLIL KALEEFLKVT MRSTRQT Biological Activity The ED50 is <3 pg/mL as measured by 7TD1 Cells. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Rat Interleukin-6 (HEK293-expressed) (rRtIL-6) to 100 μg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Rat Interleukin-6 (HEK293-expressed) (rRtIL-6) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Interleukin-6 (IL-6) is one of the most important mediators of the acute phase reaction in liver[1]. Interleukin 6 (IL-6), promptly and transiently produced in response to infections and tissue injuries, contributes to host defense through the stimulation of acute phase responses, hematopoiesis, and immune reactions. IL-6 promotes specific differentiation of na?ve CD4+ T cells, thus performing an important function in the linking of innate to acquired immune response. IL-6, in combination with transforming growth factor (TGF)-β, is indispensable for Th17 differentiation from na?ve CD4+ T cells, but that IL-6 also inhibits TGF-β-induced Treg differentiation[2]. |
| 貯存 |
- Recombinant Rat Interleukin-1 alpha (CHO-expressed)
- Recombinant Rat Interleukin-1 beta
- Recombinant Rat Interleukin-10
- Recombinant Rat Interleukin-5
- Recombinant Rat Interleukin-6 (HEK293-expressed)
- Recombinant Rat Interleukin-7, His (CHO-expressed)
- Recombinant Rat Oncostatin-M
- Recombinant Rat Stem Cell Factor (P.pastoris-expressed)
- Recombinant Rat Stem Cell Factor (HEK293-expressed)
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